Dedicate IRQ for your Sound Card and Prioritize IRQ

IRQ Sharing between Sound card and SATA/Graphic/LAN/USB IRQ is a major cause of pops and clicks. You may swap the sound card to the right slot in order to achieve "dedicate IRQ". If it doesn't work, you either buy another motherboard, or buy a MAC (this is not a joke)

Afterwards, Set IRQ priority for sound card:
1. Find out your sound card's IRQ,( Run msinfo32.exe and view hardware info)
2. In Regedit, HKEY_LOCAL_MACHINE\SYSTEM CurrentControlSet\Control\PriorityControl.
3. Add a new DWORD, "IRQ#Priority" , and the "#" in between is the sound card's IRQ. E.g. If your sound card's IRQ is 21, then the DWORD is "IRQ21Priority".
4. Set Value to 1, then Reboot